Karl Fitzpatrick has described his frightening ordeal after being diagnosed with potentially life-threatening Guillain–Barré ...

Studies now suggest that neural protein levels in serum and cerebrospinal fluid reflect axonal damage and predict poor outcome in patients with immune-mediated neuropathy, although validation ...

Axonal regrowth is a crucial process for forming a compensatory neuronal network after spinal cord injury (SCI), but this is very limited in the adult mammalian central nervous system. BioWorld ...

visualizes axons in an area-specific maturation patternin human fetal brain; visualizes aberrantly sprouting axons in neuriticplaques derived from cortico-cortical fibers in A.D. and identifies loss ...

It primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 ...

A key to their investigation was to elucidate the critical involvement of microglia in axonal degeneration post-spinal cord axon injury. Microglia are primary immune cells in the central nervous ...

This protective mechanism, dependent on the function of P2Y12 receptors, highlights a novel form of neuron-glia interaction that prevents acute axonal degeneration from spreading beyond the nodes.

The central nervous system (CNS) in adult mammals has limited regeneration capacity, and traumatic injuries to the CNS usually lead to permanent functional impairment.

This manuscript introduces DendroTweaks, a useful web application and Python library that, compared to existing modeling tools, eases interactive graphical exploration, development, and validation of ...

The plea says the petitioner's family has done its best to treat him. However, he has been confined to bed by a diffuse ...

Iluzanebart, Vigil’s lead clinical candidate, is a fully human monoclonal antibody agonist targeting human triggering receptor expressed on myeloid cells 2 (TREM2) in people with adult-onset ...