2024年6月19日，北京大学第三医院詹思延教授团队于Genome Medicine发表文章“Identifcation of novel therapeutic targets for chronic kidney disease and kidney function by integrating multi-omics proteome with ...

Department of Epidemiology and Biostatistics, School of Public Health, Chengdu Medical College, Chengdu, Sichuan, China Activin A, a cytokine belonging to the transforming growth factor-beta (TGF-β) ...

The novel drugs work by mimicking the gut hormone GLP-1, which lowers blood sugar and limits the appetite. Treatments such as ...

July 8, 2024 — By prohibiting the Activin A protein from functioning, researchers were able to halt the development of dyskinesia symptoms and effectively erase the brain's 'bad memory' response ...

In a recent study published in The Journal of Neuroscience, researchers at the University of Alabama at Birmingham uncovered ...

We have shown that dual-SMAD inhibition via small molecule inhibitors of BMP and TGFb/Activin/Nodal signaling is sufficient to trigger neural conversion. Using this technology we are particularly ...

Ditte S. Andersen continues, "We have identified activins as critical regulators of this process. In nutrient-restrictive conditions, activin signalling is strongly repressed, while it is reactivated ...

In addition to being diagnosed more frequently in older patients, pulmonary arterial hypertension (PAH) is more frequently ...

“Arrowhead believes that targeting the hepatic expression of the INHBE gene and the production of the Activin E ligand, and the adipose tissue expression of the ALK7 gene and the receptor it ...