2024年6月19日，北京大学第三医院詹思延教授团队于Genome Medicine发表文章“Identifcation of novel therapeutic targets for chronic kidney disease and kidney function by integrating multi-omics proteome with ...

The novel drugs work by mimicking the gut hormone GLP-1, which lowers blood sugar and limits the appetite. Treatments such as ...

We have shown that dual-SMAD inhibition via small molecule inhibitors of BMP and TGFb/Activin/Nodal signaling is sufficient to trigger neural conversion. Using this technology we are particularly ...

July 8, 2024 — By prohibiting the Activin A protein from functioning, researchers were able to halt the development of dyskinesia symptoms and effectively erase the brain's 'bad memory' response ...

In addition to being diagnosed more frequently in older patients, pulmonary arterial hypertension (PAH) is more frequently ...

In a recent study published in The Journal of Neuroscience, researchers at the University of Alabama at Birmingham uncovered ...

Ditte S. Andersen continues, "We have identified activins as critical regulators of this process. In nutrient-restrictive conditions, activin signalling is strongly repressed, while it is reactivated ...

However, whether BCAS2 has other functions within the nucleus remains largely unknown. Here, we show that BCAS2 is essential for primitive hematopoiesis in zebrafish and mouse embryos. The activation ...

“Arrowhead believes that targeting the hepatic expression of the INHBE gene and the production of the Activin E ligand, and the adipose tissue expression of the ALK7 gene and the receptor it ...

Serum cancer antigen 125, creatine kinase and activin A levels have been studied as possible predictors of pregnancy outcome. However, no single factor has yet been identified to predict the ...