“Having more of these precursors enables a more sustained supply of active cytotoxic CD8+ T cells for attacking tumors,” said Dr. Mittal, who is also a member of the Sandra and Edward Meyer ...
The treatment with recombinant antibodies and more recently T cell receptor (TCR) engineered T-cell therapies represent two immunological strategies that came into the forefront of clinical interest ...
Furthermore, these cells, called CAR-T cells, appear to be capable of targeting diseased cells in the tumor that do not carry this antigen, while sparing healthy cells. Glioblastoma is the most ...