TSH reference intervals should be established from the 95 % confidence limits of the log-transformed values of at least 120 rigorously screened normal euthyroid volunteers who have: ...

For more than twenty-five years, TSH methods have been able to detect the TSH elevations that are characteristic of primary hypothyroidism. Modern-day TSH methods however, with their enhanced ...

Andrew Schally, who has died aged 97, was awarded a Nobel Prize for his work isolating and synthesising neurohormones, ...

Levothyroxine sodium is the second-most prescribed drug in the United States, with approximately 25 million people using either Synthroid or generic levothyroxine to manage their hypothyroidism (low ...

The thyroid gland is controlled by the hypothalamus and the pituitary gland, which are both located in the brain. The hypothalamus releases thyrotropin-releasing hormone (TRH), which then tells the ...

The competition between Dr. Schally and fellow endocrinologist Roger Guillemin laid bare the scrambles for funding and peer recognition in scientific research and could even overshadow their ...

The white-cell count, platelet count, and blood levels of thyrotropin, glycated hemoglobin, aspartate aminotransferase, alanine aminotransferase, bilirubin, albumin, and hemoglobin were normal ...

The race was just too close to call. In 1969, Dr. Schally announced that he isolated a pinhead amount of thyrotropin-releasing hormone, which directs the pituitary gland to control the thyroid gland.

All of these factors can be obtained from hospitalized records. Biochemical variables recorded include thyroid function [free triiodothyronine (FT3), free thyroxine (FT4), thyroid stimulating hormone ...

1 Department of Clinical Genetics, Addenbrooke’s Hospital, Cambridge, UK 2 Department of Medicine, University of Cambridge, Addenbrooke’s Hospital Correspondence to: Dr S M Park Department of Clinical ...