which use milder conditioning agents than standard stem cell transplants, do not appear to damage the lungs and may help improve lung function in some patients with sickle cell disease (SCD ...

8 in Science, discovered that during the transition from lung adenocarcinoma to small cell lung cancer (SCLC), the mutated cells appeared to undergo a change in cell identity through an intermediate, ...

which use milder conditioning agents than standard stem cell transplants, do not appear to damage the lungs and may help improve lung function in some patients with sickle cell disease (SCD ...

Delivery into the LV cavity resulted in increased uptake of stem cells into the myocardium and significantly lower entrapment of donor cells in the lungs compared with IV injection (0.9±0.32 vs.

Fibrosis and accumulation of senescent cells are common tissue changes associated with aging. Here, we show that the CDK ...

Grown in a dish from human stem cells, lung organoids are multicellular, three-dimensional structures that aim to recreate key features of human tissues such as cellular complexity and architecture.

A research group from Ningbo Institute of Materials Technology and Engineering (NIMTE) of the Chinese Academy of Sciences ...

An approach considering stem cell-based therapy of CF-injured lungs should achieve a permanent correction of the CF genetic defect. Lung injury is needed for engraftment of stem cells into the lung.

So-called low-intensity blood stem cell transplants, which use milder conditioning agents than standard stem cell transplants, do not appear to damage the lungs and may help improve lung function in ...

The Lee laboratory studies the mechanisms governing homeostatic turnover and reparative programs in stem cells, with a focus on elucidating how tissue perturbations lead to lung disease. We ...

They then identified which tissues the stem cells came from. Lungs, kidneys and intestine stem cells were extracted and used to grow the organoids which had the functional features of these tissue ...

Researchers from Weill Cornell Medicine have discovered how COVID-19 can cause new cases of diabetes or worsen existing ...