Nov. 4, 2024 — Stem cells grown in microgravity aboard the International Space Station (ISS) have unique qualities that could one day help accelerate new biotherapies and heal complex disease ...
Researchers have shown that the IGFBP3 protein plays a relevant role in human lung development. The results of the study, which used organoids derived from embryonic lungs, open up new perspectives on ...
Pulmonary fibrosis causes scarring and stiffening of the tiny air sacs in the lungs, known as alveoli, making it difficult for patients to breathe. Over time, the scarring gets worse and the disease ...
"As embryogenesis progresses, this protein needs to be silenced, which tells us that it is key to maintaining lung stem cells," the researcher adds. The study has also described the interaction ...
Mesenchymal stem cells are multipotent adult stem cells that are present in multiple tissues, including umbilical cord, bone marrow and fat tissue. Mesenchymal stem cells can self-renew by ...
Stem cells are specialized cells that have the potential to develop into not one but many different types of cell. They are unlike any other cell for three specific reasons: They are unspecialized, ...
At the oncological level, IGFBP3 could also have a relevant role in lung cancer, especially in relation to cancer stem cells. “We have observed that elevated levels of IGFBP3 in lung tumour ...
Stem Cell Reports is an open access forum communicating basic discoveries in stem cell research, in addition to translational and clinical studies. Stem Cell Reports focuses on shorter ...
An approach considering stem cell-based therapy of CF-injured lungs should achieve a permanent correction of the CF genetic defect. Lung injury is needed for engraftment of stem cells into the lung.