A central question in adult stem cell biology is elucidating the signaling pathways regulating their dynamics and function in diverse physiological and age-related contexts. Muscle stem cells in ...

"We thought interferon might cause the stem cells to be killed by the immune system. But we found the retrotransposons turned on just enough interferon to activate blood cell production," said Dr.

Endothelial cells are also likely to participate in activation, both by production of cellular fibronectin and via conversion of transforming growth factor (TGF)-beta from the latent to active ...