Here, we have developed a method to insert LT-scFv into the membranes of prokaryotic and eukaryotic cells rapidly and efficiently (Fig. 1). Purified LT-scFvs are brought into contact with cells ...
FMC63, an IgG2a mouse monoclonal antibody, targets CD19. To date, a majority of the reported CART19 trials include the anti-CD19 scFv extracted from FMC63, such as both the FDA-approved CARs ...
We therefore have been developing new ways to inhibit HIV infection. In a long-term collaboration, we have created a novel method of converting nonneutralizing anti-HIV-1 envelope single chain Fv ...