Retroviruses are negative single-stranded RNA viruses in which tRNA serves as a primer for the mRNA synthesis ... that retroviral vectors offer is their ability to transform their single-stranded RNA ...
The re-transcribed DNA is then integrated into the genome ... of the encoded protein to generate a curative biological effect. Retroviral vectors integrate stably into the host genome.
Initially, T cell engineering depended on lentiviral or retroviral vectors to deliver ... known for its leading DNA synthesis technologies, recently began providing ssDNAs several thousand ...
The retroviral replication cycle requires that retroviral nucleic acids integrate into the cellular DNA of the host cell ... The RTC directs the synthesis of a double-stranded linear cDNA.
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