Retroviral vectors integrate stably into the host genome. The transgene in retroviral vectors is expressed long-term in the transduced cell and in its progeny. internal ribosome entry siteS or 2A ...
In an article published in Plos Biology, scientists show that the attachment of a retrovirus protein, called Gag, which plays a central role in the formation of viral particles, is necessary but ...
Our services for retroviruses include production of viral supernatant by transient transfection as well as assay for replication competent retrovirus. Retroviral vector-mediated gene transfer has been ...
Sequence variations in human immunodeficiency virus (HIV)-1 reverse transcriptase (RT) and protease, the molecular targets of anti-retroviral drug therapy, are prime examples of genes in which ...
Because they work differently to existing drugs, they remain active against virus that has developed resistance to other antiretroviral classes. A retroviral enzyme which converts genetic material ...
The authors used ex vivo retroviral gene transfer to constitutively overexpress VEGF in myoblasts, which were subsequently transplanted in the myocardial wall of mice. Unregulated VEGF expression ...
Adam Castillejo is still free of the virus more than 30 months after stopping anti-retroviral therapy. He was not cured by the HIV drugs, however, but by a stem-cell treatment he received for a ...
Secondary diabetes results from external factors such as prolonged use of certain medications (steroids, Anti-Retroviral Therapy), genetic conditions (MODY), or underlying health issues. Unlike ...