Our previous results indicated that human HTT undergoes alternative processing in the brains of YAC128 mice to produce HTT1a and that both full-length (FL)-HTT and HTT1a are retained in cell nuclei in ...
Breast carcinoma amplified sequence 2 (BCAS2), a core component of the hPrP19 complex, plays an important role in RNA-splicing and DNA damage. However, whether BCAS2 has other functions within the ...
However, the authors observe a redistribution of m6A mRNAs during the treatment and recovery time, with highly methylated mRNAs getting retained in the nucleus being associated with a shorter ...
Defects in RNA binding lead to genome-wide loss of ERα recruitment, particularly at weaker ERα-motifs. Furthermore, ERα mobility in the nucleus increases in the absence of its RNA-binding capacity.
The nuclear pore complex (NPC) mediates transport of all macromolecules between the nucleus and the cytoplasm ... chromatin organization and RNA biogenesis. The basket seems to recruit and ...