As Dbp5 shuttles, it could interact with Yra1 within the nucleus. The final steps in mRNA export consist of removing proteins from the mRNP and transferring the mRNA to the translation machinery.

Messenger RNA carries genetic information from DNA in the highly protected nucleus out to the rest of the cell, where structures called ribosomes can build proteins according to the DNA blueprint.

To investigate how poly(A) tails are made, the researchers created conditions where mRNAs were trapped in the nucleus to prevent ... terminating the synthesis of mRNA poly(A) tails, two of which ...

mRNA transports the most valuable cellular information—the chemical blueprint for the production of proteins—from the nucleus ...

The mRNA never goes into the nucleus of your cells where your DNA is stored. The newly made spike protein now sits on the surface of the muscle cells. Your immune system senses the spike protein ...

It is titled "Genome organization around nuclear speckles drives mRNA splicing efficiency." For a decade, researchers in the Guttman laboratory have studied how the nucleus is spatially organized ...

When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA). This process takes place in the nucleus and occurs in a series of stages. The two ...

With the help of TBWA\Chiat\Day New York, pharma giant Moderna is demystifying mRNA science for the average consumer. This ...

Moreover, we observed that expression of a chromatin regulator from an mRNA with or without its 3′UTR resulted in similar expression of the protein in the nucleus but changed the enzymatic activity of ...

Expert Rev Vaccines. 2012;11(1):55-67. A summary of the events taking place after intradermal injection of naked mRNA is given inFigure 1. Although formulation of mRNA vaccines and sophisticated ...