Analysis of human brain tissue revealed differences in how immune cells behave in brains with Alzheimer's disease compared to ...

In healthy brains, immune cells called microglia patrol for damage, clearing away debris and harmful proteins. But in the ...

More information: Hannah Scheiblich et al, Microglia rescue neurons from aggregate-induced neuronal dysfunction and death ...

Microglia affect the density of neuronal connections. Microglial cells (stained in green), the immune cells of the mouse brain, send branches into areas with many neuronal connections (stained blue).

Research from the College of Medicine provides promising insights into delaying the progression of Alzheimer’s disease for ...

thus damaging vulnerable neuron types. These effects range from the acceleration of neurodegeneration caused by mutant SOD1 acting in astrocytes and microglia to the direct production of ...

Researchers have developed a promising nasal spray therapy targeting neuroinflammation in Alzheimer’s disease, potentially ...

Their research is published in the journal Nature Communications. Stroke negatively influences interaction of microglia and ...

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“Together, these results suggest that microglia are being activated by human neuron–produced APOE4 and, in turn, are potentially helping form the misfolded protein aggregates we see in Alzheimer’s,” ...