Colchicine has a unique anti-inflammatory mechanism: it is not only able to concentrate in leucocytes, especially neutrophils, and block tubulin polymerisation, affecting the microtubules assembly, ...

Leading with practical insights from the best in the industry, the 4th Annual Inflammasome Therapeutics Summit is returning in person on November 29 – December 1 to Boston to equip you with the ...

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Halia plans to advance HT-6184 into a Phase 2 clinical trial for obesity later this year. This trial will evaluate the safety, tolerability, and efficacy of HT-6184 in combination with semaglutide for ...

This new article publication from Acta Pharmaceutica Sinica B, discusses how heme oxygenase 1-mediated ferroptosis in Kupffer ...

Impact and progress Frontiers' impact Progress Report 2022 All progress reports ...

After hours: September 26 at 6:30 PM EDT Loading Chart for VTYX ...

which leads to the activation of pro-caspase-8 downstream of TLR4 engagement. Caspase-8 cleaves and activates the NLRP1B inflammasome, thereby enhancing a cell death signal.