GS-6791, a targeted protein degrader of IRAK4, provides a differentiated mode of action compared with inhibition of kinase activity. In a poster titled ... an E3 ligase that regulates activation of ...

Shiitake mushrooms are not only a staple product in Asian cuisine, essential for ramen, dashi, or various dumpling fillings, ...

Shiitake mushrooms are not only a staple in Asian cuisine, essential in dishes such as ramen, dashi, and various dumpling ...

blocking of the ERs using fulvestrant in patients with moderately active SLE produced a significant decrease in disease activity (as measured by the SLE disease activity index score). [67] ...

Finally, proteolytic activity of MMPs can be inhibited by the tissue inhibitors of metalloproteinases, a group of proteins also produced by hepatic stellate cells. Activity grade, which represents ...