Single-cell analysis of CML patients bone marrow at diagnosis reveals coexistence of CD26-CD35+ healthy stem cells and CD26+CD35- CML stem cells, and how the ratio between these impacts TKI response.
A new approach helps examine the proportion of cancerous and healthy stem cells in patients with chronic myeloid leukemia and how this influences treatment outcomes.
RCCS San Raffaele Scientific Institute in Milan researchers have discovered that hematopoietic stem cells (HSCs) adapt their lineage commitment during gene therapy based on the underlying genetic ...
1Department of Hematology, The First Affiliated Hospital of Xiamen University and Institute of Hematology, School of Medicine, Xiamen University, Xiamen, China. 2Key Laboratory of Xiamen for Diagnosis ...
these cells are myeloid immune system cells. Most of the body’s blood cells originate in a person’s bone marrow. They become either lymphoid stem cells or myeloid stem cells, then specialize ...
Stem cells are specialized cells that have the potential to develop into not one but many different types of cell. They are unlike any other cell for three specific reasons: They are unspecialized, ...