For example, researchers have found mutations of the MTHFR gene, or methylenetetrahydrofolate reductase, to be linked to conditions like depression, bipolar disorder, certain cancers, and high ...

Polymorphisms in genes encoding proteins in two major cellular pathways influenced by MTX, namely the folate and adenosine pathways, and their association with response to MTX have been examined ...

p53 lies at the hub of a vast signalling network. Polymorphisms in upstream activators, repressors or downstream effectors of p53 might individually modulate cancer risk or interact with ...

A former DART program trainee, Khass earned his Master’s degree in Biochemistry where he focused on identifying polymorphisms in the methylenetetrahydrofolate reductase gene (MTHFR) in mothers of ...

Although no specific data to support pharmacogenetic-related birth defects were found for the NSAIDs, paroxetine and fluoxetine, it might be expected that polymorphisms modify their teratogenic ...

It illustrates balanced polymorphism because carriers are resistant to malaria, an infection by the parasite Plasmodium falciparum that causes cycles of chills and fever. The parasite spends the ...

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Individuals with MTHFR gene mutations often depend on Methylfolate supplements. These genetic changes can lead to a lack of folate, an essential nutrient that plays a crucial role in various body ...