Cite this: Targeting Ligand-gated Ion Channels in Neurology and Psychiatry: Is Pharmacological Promiscuity an Obstacle or an Opportunity? - Medscape - Mar 02, 2010.
However, the precise allosteric mechanism governing channel activation upon ligand binding, particularly the energetic changes within domains, remains poorly understood. The prokaryotic CNBD channel ...
The predicted membrane topology showed a long extracellular N terminal that presumably constitutes the ligand binding site. Homology with the Ca 2+ receptor CaSR of the parathyroid, with ...
A combination of methods, including a new method for tagging genes, demonstrates that the chemosensory co-receptors of Drosophila melanogaster (Orco, IR8a, IR25a, IR76b) are expressed widely and ...
P2Rank: Protein-ligand binding site prediction tool based on machine learning. Stand-alone command line program / Java library for predicting ligand binding pockets from protein structure.
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秋风送爽,丹桂飘香。近日(9月19日-22日),由中华医学会、中华医学会神经病学分会主办,河南省医学会承办的“中华医学会第二十七次神经病学学术会议”在美丽的郑州顺利召开。国内外知名专家学者齐聚,共享学术饕餮盛宴。神经病理性疼痛(NP)指由躯体感觉系统 ...
1 Zhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Life Sciences, Zhejiang Normal University, Jinhua, Zhejiang, China 2 Tobacco Research Institute, Chinese ...
R 425 000 Vacant Land Beverly Park This vacant plot is located in Beverly Park/Eerste River. It includes an unfinished structure/ fence and a foundation on the erf. 326 m² ...