The tumor suppressor p53 is a transcription factor involved in a variety of crucial cellular functions, including cell cycle arrest, DNA repair and apoptosis. Still, a growing number of studies ...

Recombination events in many organisms are concentrated in highly localized areas termed 'hot spots'. Hot spots can be detected by statistical analysis of genetic variation, analysis of pedigrees ...

This is an important study examining the role of conserved PCH-2 protein at different stages of C. elegans meiosis. The authors use elegant molecular genetic approaches to provide convincing evidence ...