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Immunity|组织驻留Treg:定植特化模型vs 泛组织模型
引言组织驻留性免疫细胞对维持机体稳态和对抗感染具有重要意义。然而,我们对于组织驻留免疫细胞的构成和特性仍缺乏足够的理解。关于组织驻留免疫细胞的认识大多来自巨噬细胞的研究,在胚胎发育早期,造血祖细胞种植在各种组织并特化发育为独特的巨噬细胞【1】。组织驻留性记忆细胞(tissue-resident ...
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