The Heart Outcomes Prevention Evaluation (HOPE) study was a landmark study employing the angiotensin-converting enzyme (ACE) inhibitor ramipril in a patient population predestined for vascular events.

ACE inhibitors are best known for treating high blood pressure. They work by targeting the hormone angiotensin II. Angiotensin-converting enzymes (ACE) inhibitors help blood vessels to relax and ...

2 Department of Business Information Systems, University College Cork, Cork, Ireland 3 Department of Pharmacology and Therapeutics, University College Cork, Cork, Ireland 4 Mercy University Hospital, ...