These biofilms act as thick barriers, limiting the entry of drugs, and helping the bacteria become resistant to antibiotics .

Most of the disease-causing bacteria secrete matrix-like layers around themselves called biofilms. These biofilms act as ...

These biofilms act as thick barriers limiting the entry of drugs and helping the bacteria become resistant to antibiotics ...

Drug discovery has undergone major transformations ... products with therapeutic benefit (such as the use of cardiac glycosides extracted from plants of the genus Digitalis), to the systematic ...

Medications are the mainstay of treatment for multiple sclerosis (MS). Many of them are used to block the immune system's attack on the nerves and slow or prevent progression and relapses (flare-ups) ...

State Key Laboratory of Fine Chemicals, Dalian University of Technology, 2 Linggong Road, 116024 Dalian, China School of Chemical Engineering, Dalian University of Technology, 2 Linggong Road, 116024 ...

but it suffers from serious toxicities and low efficacy against drug-resistant disease. Here, Satomaa and colleagues have developed a novel ADC, GLK-33, utilizing lintuzumab antibody and a hydrophilic ...

Using this approach revealed a drug resistance feedback loop in high-grade serous ovarian cancer, suggesting that combining phosphatidylinositol 3-OH kinase, protein kinase B and mammalian target ...

Subplenones A-J: Dimeric Xanthones with Antibacterial Activity from the Endophytic Fungus Subplenodomus sp. CPCC 401465.

Carbohydrate chemistry deals with the reactions and synthesis of, often biologically important, carbohydrate molecules including monosaccharides, polysaccharides and their derivatives ...

XBJ, a Chinese herb-derived therapeutic, has been approved for sepsis treatment in patients who are critically ill (China Food and Drug Administration (China FDA); Beijing, China, No Z20040033). The ...