In The Lancet Respiratory Medicine, Olivier Sitbon and colleagues1 present the results of a randomised, phase 2b clinical trial (ELEVATE-2) that compared the safety and efficacy of pulmonary arterial ...

Emerging research has linked COVID-19 to joint pain and osteoarthritis, but the precise mechanisms behind this connection and ...

The European approval comes months after the FDA’s approval of the first-of-its-kind treatment for pulmonary arterial ...

BQ-3020 是一种内皮素受体 (endothelin receptor) (ETBreceptor) 激动剂，取代[125I]ET-1 与猪小脑 ETB 受体结合，IC50 值为 0.2 nM。BQ-3020 引起兔肺动脉血管收缩和猪膀胱颈松弛，可用于心血管疾病研究。 BQ-3020是一种内皮素受体（ETB receptor）激动剂，能够取代125IET-1与猪小脑ETB ...

Two abstracts win the prestigious AHA 2024 Paul Dudley White International Scholar Award Allschwil, Switzerland - September 5, 2024Idorsia Ltd (SIX: IDIA) today announced that new data on aprocitentan ...

Two abstracts win the prestigious AHA 2024 Paul Dudley White International Scholar Award Allschwil, Switzerland – September 5 ...

The Endothelin B Receptor pipeline drugs market research report outlays comprehensive information on the Endothelin B Receptor targeted therapeutics, complete with analysis by indications, stage of ...

The key targets in the Alport Syndrome pipeline products market include Endothelin 1 Receptor (Endothelin A Receptor or EDNRA), Dystrophin (DMD), and Free Radical. Alport syndrome is a genetic ...

Endothelin 1 (swine, human) 是具有人和猪内皮素1序列的合成肽，是有效的内源性血管收缩剂。Endothelin 1 通过两种类型受体ETA和ETB发挥作用。 Endothelin-1（ET-1），无论是在人类还是猪体内，都是一种高度保守且具有显著生物活性的多肽，属于内皮素家族的关键成员。