Abstract Prognosis in Acute Drug-induced Liver Injury Liver Injury Pattern Presentation and DILI Outcome Chronic Liver Disease as a DILI Outcome References Chronic Liver Disease as a DILI Outcome ...
Drug-induced liver injury (DILI) is common because it can be caused by different pharmacological agents from nearly all classes of medications, including hepatotoxic drugs, anesthetics, anticancer ...
Drug-induced liver injury including cholestasis is another form of acquired liver disease, accounting for approximately 2 to 5% of hospitalizations for jaundice, 10% of cases of hepatitis in all ...
It is generally accepted that IL6-mediated STAT3 signaling in hepatocytes, mediated via glycoprotein 130 (gp130; IL6ST), is beneficial and that the synthetic IL6:IL6ST fusion protein (HyperIL6) ...
Recent draft guidance highlights the challenges that industry and regulators face to predict rare drug-induced liver injury. At the end of August 2008, the consultation period ended for comments ...
"The Drug Induced Liver Injury Network (DILIN), a multicenter U.S. observational program that collects and analyzes data from patients with hepatotoxic effects attributed to various drugs and HDS ...
“Applying multi-omics to cancer is relatively easy,” says biologist Jean-François Deleuze, coordinator of The Laboratory of Excellence in Medical Genomics (GENMED) and director of the ...