A Seattle biotech company is working on a tweak to gene expression that could shut down hepatitis B (HBV), one of the viruses ...

Plasma samples were assessed for NET markers, including cell-free DNA (cfDNA) and histone-DNA complexes, along with DNase ...

Her group investigates chromatin dynamics during DNA replication and repair. The Mattiroli group uses biochemical reconstitutions, structural approaches and cell biology to elucidate the biophysical ...

Epigenome editing demonstrates that DNA methylation can impact certain histone marks, helping control proper gene expression dynamics. Here the authors show that DNA double-strand breaks move ...

Researchers from the Mattiroli group have found that the way DNA is packaged in cells can directly impact how fast DNA itself is copied during cell division. They discovered that DNA packaging sends ...

Portal vein thrombosis (PVT) is a challenging complication in liver cirrhosis, with no currently available sensitive ...

The histone proteins of complex cells are named H2A, H2B, H3 and H4. They are assembled into groups of eight, around which a ...

The good news is that drugs called CHK1 inhibitors were found to selectively destroy tumor cells containing ecDNA in mice ...

Cancer continues to be one of the most challenging diseases due to the complex molecular mechanisms involved. Epigenetic modifications, particularly histone modifications, play a crucial role in ...

Lytic induction therapy has been developed to selectively kill EBV-positive cancer cells by triggering viral reactivation ...

Background:Gastrointestinal (GI) cancer encompasses a group of malignancies affecting the digestive tract and related organs, including cancers of the colon, pancreas, stomach, liver, and esophagus.

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