Objectives Myofibroblasts are key effector cells in the extracellular matrix remodelling of systemic sclerosis-associated interstitial lung disease (SSc-ILD); however, the diversity of fibroblast ...

Here, we aimed to revisit the role of the tumour microenvironment as a physical barrier for gemcitabine delivery. Results Gemcitabine accumulation was significantly enhanced in fibroblast-rich tumours ...

This study provides abundant valuable scRNA-Seq data that profiles fibroblasts involved in myocardium and coronary vasculature development. However, the evidence supporting the authors' claims is ...

Objectives Fibroblasts in synovium include fibroblast-like synoviocytes (FLS) in the lining and Thy1+ connective-tissue fibroblasts in the sublining. We aimed to investigate their developmental origin ...

1 Cancer Center, Renmin Hospital of Wuhan University, Wuhan, Hubei, China 2 Institude of Experimental Immunology, University Clinic of Rheinische Friedrich-Wihelms-University, Bonn, Germany Lung ...

Figure 3. The mechanism of action of P4HA1 in various cardiovascular diseases. P4HA1 is involved in regulating the proliferation of fibroblasts and the synthesis of collagen in various cardiovascular ...

3Division of Cancer Biology, Laboratory Animal Center, Fourth Military Medical University, Xi’an, China.