Lumbar disc herniation is one of the most common structural changes in the lower back and the most common cause of radiating pain, or sciatica, in the leg.
Pain-sensing neurons exchange signals with immune cells that drive endometriosis, sparking the pain associated with the condition, new research suggests.
One class of drugs has already found success in treating the painful, disorienting and common attacks. Excitement is building about a slew of additional drug targets.