We then discuss the potential of MSCs for articular cartilage repair in patients with OA, with particular respect to the chondrogenic differentiation potential of MSCs, and review the currently ...

Experiencing age-related diseases such as stroke, osteoarthritis, and diabetes can be profoundly challenging. Current ...

These cells do express human β2m. This model only mimics the chondrogenic part of endochondral bone formation. In the monolayer experiments, we also tested direct osteogenic differentiation. Also in ...

Tissue engineering using stem cells represents a promising approach to repair bone damage caused by aging and trauma. However, the exact mechanisms behind the differentiation of skeletal stem cells ...

(2020). Investigation of multiphasic 3D-bioplotted scaffolds for site-specific chondrogenic and osteogenic differentiation of human adipose-derived stem cells for osteochondral tissue engineering ...

Methods scRNA-seq was used to identify cell subsets and their gene signatures in healthy human and degenerated meniscus cells to determine their differentiation relationships and characterise the ...

The core has both scanning electron microscopes (SEM) and transmission electron microscopes (TEMs). The TEMs are 120-kilovolt instruments used for both clinical and research samples. Standard ...

The selection of material and manufacturing methods for biomedical implants is crucial when considering the specific locations and movement conditions of structures like joints and bones in the human ...

We have already extensive experience both in skeletal and neural stem cell differentiation. Refinement of the growth plate model from iPSCs will be built on our current chondrogenic spheroid culture ...