Researchers from the Josep Carreras Leukaemia Research Institute have found that the efficacy of varni-cel, a CAR-T infusion ...

The field of engineered cell therapies is rapidly advancing, offering promising new treatments for autoimmune conditions and cancer. Recent applications, particularly the use of chimeric antigen ...

“Most notably, we will be showcasing what we believe to be the first iPSC-derived CD4+ and CD8+ CAR T cells that demonstrate function comparable to primary αβ CAR-T cells. The engineerability of ...

The development of CAR-T cell therapy marks a major breakthrough in cancer treatment. These “living drugs” are T-cells genetically engineered to spread through the body, identify, and destroy cancer ...

A new study now explores how activated CD8 + effector T cells handle ammonia, and how this impacts the survival and function of these cells. CAR-T cells are revolutionizing the treatment of cancer ...

CD4-cell counts and T-cell activation levels were determined ... and higher LPS levels were associated with greater activation of CD8 + lymphocytes. CD8 + activation also was found to be higher ...

The development of CAR-T technology in recent years has been a major milestone in the fight against cancer. These sort of ...