T cells are a type of white blood cell that is central to your immune defense. There are four types which serve different functions: This article will guide you through how CD4 and CD8 cells interact, ...

Researchers from the Josep Carreras Leukaemia Research Institute have found that the efficacy of varni-cel, a CAR-T infusion ...

The development of CAR-T cell therapy marks a major breakthrough in cancer treatment. These “living drugs” are T-cells genetically engineered to spread through the body, identify, and destroy cancer ...

撰稿 | 郑诗蔚   责编 | 周叶斌近年来，靶向CD19的CAR T细胞疗法在治疗儿童和青少年复发或难治性急性淋巴细胞白血病（ALL）方面卓有成效，但约一半的患者在CAR ...

Company to share preclinical data across diverse pipeline of iNK, γδ iT, and αβ iT cell therapy programs for oncology and autoimmune disease ...

The development of CAR-T technology in recent years has been ... In the infusion product, a threefold or higher amount of CD4 ...

【导读】针对肿瘤特异性新抗原的免疫治疗具有潜力，但它们在肿瘤细胞上的超低表达，对T细胞治疗提出了挑战。在这项研究中，团队发现，嵌合抗原受体（CARs）在针对人类白细胞抗原（HLA）I类呈现的p53R175H新抗原时，其敏感性比T细胞受体（TCRs）低 ...

The development of CAR ... the CAR-T cells into the patient after treatment. Taken together, these results encourage a better-quality control of the infusion products, focusing on the CD4 vs.

Construction of CAR or other engineered T cell receptors - Traditional and innovative CAR structural designs - Practical aspects of screening and manufacturing CAR therapies - Feasibility studies in ...

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