University of Washington-led research, published in 2023, discovered microglia in the brains of people with Alzheimer's ...

Additional characterization of their connectivity systematically reveals the molecular-genetic diversity of cell types in the entire brain. Using single-cell and single-nucleus RNA sequencing ...

Hunger" neurons expressing the AGRP gene (red), alongside newly-discovered "satiety" neurons expressing the BNC2 gene (green) ...

Recent research has revealed that alcohol use disorder and Alzheimer’s disease share significant patterns of gene ...

Strokes lead to irreversible damage to the brain and are one of the most common ... used single-cell RNA sequencing in animal ...

New research from Scripps Research links Alzheimer’s disease and alcohol use disorder, showing similar gene expression ...

Furthermore, integrative transcriptomic analysis (RNA-seq) showed that the combination therapy activates the Wnt signaling ...

Researchers discovered alcohol use disorder (AUD) and Alzheimer's disease (AD) exhibit similar patterns of gene dysregulation, hinting that alcohol consumption may hasten Alzheimer’s progression.

Recently, we developed a single-nucleus RNA-seq method in flies (McLaughlin ... systemic inflammatory signals and gut-brain interactions. We will apply single-cell sequencing and cell surface ...