In healthy human brains and brain organoids, neural stem cells develop into nerve cells (or neurons), which send and receive messages throughout the brain, as well as into various types of glial ...
Researchers have created "mini-brains" using stem cells from patients with a rare form of autism, allowing them to study brain development in detail. These organoids revealed how a genetic mutation in ...
Such brain “organoids,” as they’re called, have always raised ethical questions. But when I learned that some of them had spontaneously developed optic vesicles—that is, precursors to eyes—I realized ...
Methods: In this study, we generated brain organoids from induced pluripotent stem cells (iPSCs) derived either from a GLUT1-DS patient or a healthy individual. The functional organoids were analyzed ...
Brain organoids hold great promise in recapitulating human neurological diseases, which might help overcoming limitations in the translation of research findings into clinical progress. However, while ...
The lab-grown organoids allowed the team to gain a new understanding of how one genetic mutation leads to autism spectrum disorder. It also showed that an experimental drug, called NitroSynapsin, ...