Pompe disease is characterized by a deficiency of acid α-glucosidase (GAA). The GAA enzyme degrades lysosomal glycogen, and insufficient GAA activity causes glycogen to accumulate in various tissues.

11.3. The Advisory Committee recommended that avalglucosidase alfa for the treatment of late onset Pompe disease be funded with a medium priority.

Some popular options include metformin, alpha-glucosidase inhibitors ... and alpha-lipoic acid. However, more research is needed to determine their effectiveness and proper dosages.

POMBILITI in combination with OPFOLDA is indicated for the treatment of adult patients with late-onset Pompe disease (lysosomal acid alpha-glucosidase [GAA] deficiency) weighing ≥40 kg and who are not ...

B073Q157ZH It contains 500 mg of naturally occurring chlorogenic acid, which boosts the natural, plant-based green coffee extract and prevents the synthesis of the carbohydrate-digesting enzyme ...