Myeloperoxidase activity in skin was measured essentially as described 9 except that supernatants from skin homogenates were 'normalized' for protein concentration before assay. Data are expressed ...
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a systemic autoimmune disease characterized by the inflammation of blood vessels, and it has been demonstrated that ...
However, the antigen involved is not proteinase 3 or myeloperoxidase but LAMP-2. This molecule, a heavily glycosylated type I membrane protein, was first reported as a target of ANCA in patients ...
Other clinical features include: The patient has the following antibodies: P-ANCA positive with perinuclear pattern (anti-myeloperoxidase [MPO]). He is negative for C-ANCA antibodies (serine ...