Transposon Therapeutics, a biotechnology company developing a platform of novel, orally administered therapies for the treatment of neurodegenerative and aging-related diseases, including Alzheimer's ...

Transposons Can Encode siRNAs That Mediate Their Own Silencing Because transposon movement can be destructive, it is not surprising that most of the transposon sequences in the human genome are ...

【编者按】在上海市科学技术委员会资助（项目编号：22DZ2304300）下，澎湃新闻联合《世界科学》对获得国家及上海市科技奖励的成果进行科普化报道。 本篇报道围绕2022年上海市自然科学奖 ...

For the past decade, scientists have relied almost exclusively on CRISPR-Cas systems for genome editing. Now, a smaller but ...

Making complex proteins and unique biological entities is getting increasingly complex. A generalized CHO host may not be the ...

These tissue models, known as "organoids," are at the cutting-edge of bioengineering. "We then used a high throughput screening technique called transposon-insertion sequencing (Tn-seq), combined with ...

To streamline the workflow, increase throughput and reduce sample loss, Epicentre has developed Nextera ™ technology, a transposon-based method for preparing fragmented and tagged DNA libraries ...

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ...

"We then used a high throughput screening technique called transposon-insertion sequencing (Tn-seq), combined with metabolic modeling and live imaging, to study how P. aeruginosa adapts to ...

Scientists at St. Jude Children's Research Hospital have revealed how Fanzor2's divergence from bacterial ancestors may make ...

Koi betta fish were bred from marble bettas for an even more distinct look. The marbling comes from a gene called a transposon that destabilizes pigmentation and can change over time. To maintain the ...

导  读开发大片段DNA精准插入技术是基因组编辑研究领域的热点之一。最近，研究人员开发了一种新的植物基因组大片段DNA精准插入技术——TATSI。该技术利用DNA转座子可在基因组中进行“剪切”-“粘贴”的特性，通过将水稻中的mPing/Pong ...