Novel method identified protein degraders that target Pin1, a protein involved in pancreatic cancer development.

In drug discovery, targeted protein degradation is a method that selectively eliminates disease-causing proteins. A ...

SOMAmer reagents are synthetic ssDNA sequences with hydrophobic appendages that tightly bind a specific protein target, enabling unprecedented multiplexing power across a 10-log dynamic range. Unlike ...

DNA is negatively charged, due to the phosphate groups in its phosphate-sugar backbone, so histones bind with DNA very tightly. The basic repeating structural (and functional) unit of chromatin is ...

The Somascan Assay uses Slow Off-rate Modified Aptamers (called SOMAer regents) to provide 7,000 highly reproducible measurements (-5% CV) of circulating proteins from a single, 55 ul sample of plasma ...

The Onion buys Infowars{beacon} 12:30 REPORT It’s Thursday. Can you believe the election was only nine days ago? It feels ...

Lyft's Q3 earnings exceeded expectations, with 32% y/y revenue growth to $1.52B & 16% y/y gross bookings growth. Read why I ...

UCSF researchers develop customizable SNIPR sensors that activate engineered cells only near tumors, promising precise cancer ...

Masturbation isn’t something any of us should be shy about, but when the mood strikes, some of us seize it a little too tightly. To put it plainly, if you’ve got a penis, grabbing it too hard ...

Antibodies bind to specific antigens on pathogens ... Once bound, the antigens - and the substances they are found on - are merged tightly together. This makes them easier to identify and deal ...

Gabe Vasquez will keep his seat in Congress in New Mexico's hotly contested 2nd Congressional District, according to unofficial results. Both Vasquez and his Republican challenger Yvette Herrell ran ...