This shift in focus brings attention to prodrugs – medications that start as inactive or less active, and once inside the ...

Prodrugs are medications that start as inactive or less active, and once inside the body, are converted into the active form, ...

Researchers from IOCB Prague have succeeded in preparing compounds capable of activating prodrugs at predetermined locations in the body, enhancing their effectiveness and expediting their action.

Join us for the final broadcast of this year's symposium as John Higgins explains how prodrugs can be pursued early in discovery space in order to optimize drugs’ physicochemical and biopharmaceutical ...

Experiments in which they tested the effectiveness of activating the prodrugs in cell culture on colon and prostrate cancer cells showed the antibody to be effective at therapeutically relevant ...

MAIA will present the results of preclinical studies for its new THIO-based prodrugs, designated as MAIA-2021-20 and MAIA-2022-12, which are lipid-conjugated compounds derived from THIO.

The Danish pharma group is pledging $285 million in upfront and milestone payments for the lead GLP-1 asset in the ...

In relief to Bristol-Myers Squibb Holdings Ireland (BMS), the Delhi High Court has upheld its patent for the anti-cancer drug ...

NanoViricides, Inc. (NYSE Amer.: NNVC ) (the “Company”), a clinical stage global leader in broad-spectrum antiviral ...

The US Food and Drug Administration (FDA) has approved foscarbidopa and foslevodopa (Vyalev, AbbVie), a solution of carbidopa and levodopa prodrugs for 24-hour continuous subcutaneous infusion ...

The drug will be marketed under the trade name Vyalev. Vyalev is a solution of carbidopa (CD) and levodopa (LD) prodrugs, which are the standard of care for PD patients. Prodrugs are medications ...

In addition to the MIC platform, Nammi has also developed a nanoparticle platform to deliver Immune Modulating Prodrugs (IMPs) using their Nammisome technology. Multiple Nammisome clinical candidates ...