AKT signaling pathway is one of the most critical and extensively investigated signaling pathways. It is the central ...

A precursor of vitamin K may help slow down prostate cancer progression, a recent study conducted in mouse models of suggests ...

The study’s findings paint a vivid picture of cellular destruction. Menadione works by inhibiting a crucial lipid called ...

The 370 kDa ATM protein has been suspected of possessing kinase activity because of its substantial similarity to proteins belonging to the phosphatidylinositol 3-kinase (PI3-K) family ...

Work at Reactive Biosciences Inc. has led to the discovery of new phosphatidylinositol 3-kinase α (PI3Kα) (H1047R mutant) inhibitors reported to be useful for the treatment of cancer. PI3Kα (H1047R ...

Further confusion can be caused by splice variant nomenclature: a recent example is phosphatidylinositol phosphate kinase type 1, referred to variously as PtdInsPKIγ-90 (denoting molecular weight ...

1000528 (2009) 5.Atsushi Suenaga, Naoki Takada, Mariko Hatakeyama, Mio Ichikawa, Xiaomei Yu, Kentaro Tomii, Noriaki Okimoto, Noriyuki Futatsugi, Tetsu Narumi, Mikako Shirouzu, Shigeyuki Yokoyama, ...

The research team examined the role of a lipid—phosphatidylinositol 4,5-bisphosphate, or PIP2—in regulating the SK2 channel.

Journal of Neurophysiology; 116:658-70. Glovaci, I., Chapman, C.A. (2015) Activation of phosphatidylinositol-linked dopamine receptors induces a facilitation of glutamate-mediated synaptic ...

Research analysts at StockNews.com assumed coverage on shares of MEI Pharma (NASDAQ:MEIP – Get Free Report) in a report issued on Wednesday. The brokerage set a “buy” rating on the stock. Other ...

We report here for the first time that high-fat feeding augments plasma LPS at a concentration sufficient to increase body weight, fasted glycemia, and inflammation. LPS infusion in normal diet ...