Phosphatidyl inositol 3-phosphate (PI3) kinase and PTEN (phosphatase and tensin homolog) are two other players that seem connected to HER2. Mutations in PI3 kinase occur in 30% of breast cancers ...
Our recent studies also show that we can engineer the small CDR H3 domains of certain anti-HIV monoclonal antibodies into potent and broad inhibitor of infection when coupled to the surface of ...