亲核取代反应(Nucleophilic substitution)指带有负电或弱负电的亲核体攻击(或撞击)并取代靶分子上带正电或部分正电荷的碳核的反应。 Ø 反应速度只取决于一种化合物浓度的反应，在动力学上称为一级反应 Ø 反应速度取决于两种化合物浓度的反应，在动力学上称为 ...

The most accepted model to explain this property of lentiviruses is that nucleophilic virion proteins chaperone viral nucleic acids across the nuclear envelope. A recent study by Zennou and ...

For example, alcohols can undergo nucleophilic displacements of the hydroxyl functionality, carboxaldehydes can participate in condensations with primary amines to form enamines and carboxylic ...

Researchers developed a highly selective fluorescent probe to image serotonin in cells and animal models, shedding light on ...

Afterward, facilitated by proximity, a second bond is formed (nucleophilic reaction between an amino group in serotonin and a ...

Constructing complex molecules from simpler ones is pivotal for the development of pharmaceuticals, materials science, and ...

Handgraaf, Jan-Willem van Erp, Titus S and Meijer, Evert Jan 2003. Ab initio molecular dynamics study of liquid methanol. Chemical Physics Letters, Vol. 367, Issue. 5-6, p. 617.

What is the difference between Undergraduate Research (UR) and Undergraduate New Investigator (UNI) grant proposals? UNI proposals are limited to faculty researchers in the first five years of their ...

This led the team to investigate using a new click ‘connecting hub’ – thionyl tetrafluoride gas (SOF 4). This ‘hub’ molecule was first reported in 1902 and has four replaceable fluoride sites for ...

Serotonin in depression is highly relevant in diagnosis, treatment, and drug development. To better study this area, a Chinese team has now developed a fluorescent probe for imaging processes that is ...

MK-STYX is a novel protein included in the dual specificity mitogen-activated protein kinase phosphatase class that lacks the essential nucleophilic cysteine required for phosphatase activity.

Serotonin in depression is highly relevant in diagnosis, treatment, and drug development. To better study this area, a Chinese team has now developed a fluorescent probe for imaging processes that is ...