The movement of proteins within the nucleus can occur by diffusion, with surprisingly extensive and rapid turnover occurring in high-affinity intranuclear compartments. The transport of the ...

This handbook contains a comprehensive collection of protocols to streamline imaging workflows and ensure reproducible ...

development of a method that allows long-term intracellular and intranuclear tracking of gene therapeutics and gene delivery vectors; design of safe, efficient and stable non-viral gene delivery ...

PROG and its metabolites can upregulate gene activity through their direct actions on the PROG intranuclear receptor, but they can also act at the NMDA receptor to reduce excitotoxicity and at the ...

Q3 2024 Earnings Call Transcript November 7, 2024 NuScale Power Corporation misses on earnings expectations. Reported EPS is ...

XPOVIO ® is the world's first approved orally-available, selective inhibitor of the nuclear export protein XPO1. It offers a novel mechanism of action, synergistic effects in combination regimens, ...

The cloning of green fluorescent protein (GFP), engineering of chimeric fusion proteins, and advances in fluorescence imaging methods have made it possible for researchers to follow the dynamics ...

It offers a novel mechanism of action, synergistic effects in combination regimens, fast onset of action, and durable responses. By blocking the nuclear export protein XPO1, Xpovio can promote the ...

Another and important means of prevention of neurologic disease after spinal anesthesia involves the proper selection of patients. Afflictions of the central nervous system and spinal column are ...

Shih, and Wei-Heng Shih, “Efficient Intranuclear Gene Delivery by CdSe Aqueous Quantum Dots Electrostatically-Coated with Polyethyleneimine,” Materials Research Express, 2, 015401 (2015) Cheng-Hsin Lu ...

What's more, hyperscalers have made commitments to customers and shareholders for meeting their accelerating power demands with carbon-free energy. Intranuclear, and in particular, small module ...