The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone proteins and about 146 base pairs of DNA (Van Holde, 1988; Wolffe, 1999).

▎药明康德内容团队编辑  本周，顶尖学术期刊《自然》及旗下《自然-医学》《自然-癌症》《自然-方法》等一系列子刊联手带来一项重磅专题：人类肿瘤图谱网络计划（HTAN）的最近进展。这一计划从2018年启动，旨在为肿瘤及其周边环境构建单细胞分辨率的三维图 ...

In eukaryotes, genomic DNA is stored in the nucleus as nucleosomes, interacting with a set of proteins, forming a molecular complex called chromatin. The proper folding of the chromatin structure ...

2024年10月24日至27日，备受瞩目的第57届美国肾脏病学会（ASN）——肾脏周（Kidney Week），在风景宜人的美国圣地亚哥盛大召开。此次盛会由ASN精心筹备并主办，是全球肾脏病学领域内规模最大、学术权威性最高的顶级会议之一。

Fearful memories are known to recruit neurons in a specific region of the brain called the amygdala. When we experience something frightening, the amygdala signals to other brain regions involved in ...

研究者在一种参与脂肪醛氧化的酶附近发现了一种假定的因果变异，并在酵母中测试了这种基因，以确认其产生色素变化的能力。研究中广泛的生化和遗传学工作有助于人们了解非模式生物的颜色，为未来对鹦鹉和其他鸟类色素沉着的研究打开大门。

The histone proteins of complex cells are named H2A, H2B, H3 and H4. They are assembled into groups of eight, around which a ...

Researchers from UAB and Iowa State University have produced the first-ever genome assemblies of two hidden-neck turtle ...

A new study on dogs found that chromatin's spatial structure has a significant role in the evolution of social behavior.

Transcription activation of genes by estrogens is driven by enhancers, which are often located within the same Topologically Associating Domain (TAD) as non-targeted promoters. We investigated how ...

We specialize in high throughput top down liquid chromatography-mass spectrometry. This allows us to study chromatin biology with proteoform level specificity and observe quantitative changes to ...