Mirvetuximab soravtansine was the first ADC to show efficacy as a therapy for platinum-resistant ovarian cancer. Despite high ...
These properties led Lee and colleagues to investigate cadherin molecule functioning in synovial lining and in autoimmune arthritis. Initial investigations in healthy mice demonstrated that ...
One of the major constituents of the cell-adhesion complex in epithelial cells is E-cadherin, a transmembrane protein involved in homotypic cell–cell adhesion. E-cadherin exerts a potent ...
Subsets of macrophages have been found to closely associate with cells about to metastasize in the breast tumor ...
《Aging》杂志已完成对本文的调查。我们发现图5C中显示菌落形成实验的面板存在多处外部重复。作者重复使用了另一项研究中已发表的菌落形成实验数据 [1]，并在之后发表的文章 ...
According to experts, a mutation in the cadherin 1 gene or CHD1 increases a person’s risk of developing stomach cancer early at an average age of 38 years. Doctors say in stomach cancer, you will ...
A: Animal; ACE: Accessory cholera enterotoxin; H: Human; ZOT: Zonula occludens toxin.
AFDN作为粘附连接的支架蛋白，可以募集cadherin或连接蛋白，并与actin相互作用，促进粘附连接的形成。AFDN在肿瘤中的作用首次在急性髓性白血病中被 ...
Proteomic analysis of tunneling nanotubes (TNTs) identifies CD9 and CD81 as major positive regulators of TNT formation.
Image shows 3D human jejunal intestinal organoid infected with human rotavirus. Red is rotavirus, green is E-cadherin and blue are nuclei. Targeted mutation via reverse engineering answers critical ...
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