5-trisphosphate (PtdIns(3,4,5)P 3). Enhancement of FcγRIIB-mediated inhibition is of considerable interest for the development of novel therapeutic approaches. The high-affinity Fc receptor for ...

More biochemical details are known about the adaptation mechanism. It was found that inositol 1,4,5-trisphosphate is a messenger for the release of calcium ions from the intracellular stores and that ...

The characteristics of a second main signaling pathway that used the phosphoinositide-derived second messengers diacylglycerol and inositol trisphosphate were just beginning to be described.

Abstract and Introduction Rationale for i.v. Antihypertensive Selection Clinical Pharmacology of i.v. Antihypertensives References There are potential concerns with the use of sodium nitroprusside ...

Platelets are anucleate cells that play an essential role in thrombosis and haemostasis. They express all four Class I Phosphoinositide 3-kinase (PI3K) isoforms, each of which can catalyse the ...