and the tuberous sclerosis (TSC) complex–mammalian target of rapamycin (mTOR) pathway. GSK3 as pleiotropic roles in controlling axon outgrowth depending on the substrates involved. Local ...

The opposite effect was observed in cells that were deficient for the tuberous sclerosis complex (TSC; an endogenous negative regulator of mTOR activity), in which mTOR is hyperactive: Tsc2 − ...

Marinus Pharmaceuticals has reported that the Phase III TrustTSC trial of oral ganaxolone in treating seizures linked to ...

A Murrells Inlet family is back from a trip to Capitol Hill advocating to continue research funding for a rare disease called Tuberous Sclerosis Complex. Heather Harden said her daughter Nell was only ...

More than 20 rescued and disabled animals, including donkeys and goats, have recently taken shelter in a newly established animal sanctuary within The Sustainable City (TSC) complex in Dubai.

(NASDAQ:MRNS) stock plunged after the company revealed disappointing data from the Phase 3 TrustTSC trial of oral ganaxolone for seizures associated with tuberous sclerosis complex (TSC ...

Upsher-Smith Laboratories, LLC (Upsher-Smith) today announced that it will attend the 2024 Child Neurology Society (CNS) ...

In Marnius’ TrustTSC study, Ztalmy (ganaxolone) didn’t meet its primary endpoint of percent change in tuberous sclerosis complex (TSC)-associated seizure frequency, the company reported.

The event will raise funds to further tuberous sclerosis complex (TSC) research and expand support programs for individuals and families affected by the disease. Formed in 1974 by four mothers ...