In most cases rheumatoid arthritis begins insidiously. Signs and symptoms develop slowly ... such as the ones in the fingers and toes. How many joints are affected varies considerably.

For many people with RA, the first symptoms will be pain in one joint, or in the fingers, wrists, toes, and ankles ... to do ...

feet, and ankles. Symptoms of RA often start between the ages of 20 and 50, but they can also affect young children and older adults. Related: Rheumatoid Arthritis Age of Onset The earliest signs of ...