I read with interest the “What's your diagnosis? Limb discoloration on a depressed tree frog (Hyla cinerea)” in Lab Animal, Vol. 34, No. 3. As a superintendent of herpetology at the Bronx Zoo ...

The health service highlights that swelling in the legs is a red flag for heart failure. This is a condition known as oedema, which can also impact the feet and ankles, making walking difficult.