本研究首次阐明了在AU患者中存在上调的HDACs，并详细阐述可能的致病机制。研究者证实了HDACs通过调节CDK6/ID2轴促进Th17细胞分化和致病性，从而促进AU炎症。该研究为HDACs及其下游分子作为AU和其他自身免疫性疾病的潜在治疗靶点提供了 ...

A machine-learning method predicts whether a genetic variant is pathogenic and affects certain human tissues. The ...

With the onset of climate change, new microbial threats are emerging that can compromise food safety and quality, lead to environmental degradation, and have an overall adverse effect on human health.

Overall, the novel APEC strains exhibited different degrees of pathogenicity in both in vivo and in vitro assays. Some strains showed high virulence in all assays while some were less virulent ...

A study out of the University of New South Wales (UNSW) has found that high-pathogenicity avian influenza virus (HPAIV) H5N1 ...

[Courtesy of Sasner et al., 2024.] Carter chose these variants based on five criteria: how well the wild-type allele is ...

The H5N1 virus, initially restricted to Eurasia and Africa, has since spread to North and South America and even reached ...

A new study from College of Veterinary Medicine researchers finds the first genetic evidence of feline coronavirus (FCoV) ...

Nature Communications has published and made public an extensive report with full results on field sampling and diagnosis of ...

The following is a summary of “Pan-genome analysis reveals novel chromosomal markers for multiplex PCR-based specific detection of Bacillus anthracis,” published in the September 2024 issue of ...