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上海交大团队发现葡萄膜炎发病新机制和治疗新思路
本研究首次阐明了在AU患者中存在上调的HDACs,并详细阐述可能的致病机制。研究者证实了HDACs通过调节CDK6/ID2轴促进Th17细胞分化和致病性,从而促进AU炎症。该研究为HDACs及其下游分子作为AU和其他自身免疫性疾病的潜在治疗靶点提供了 ...
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